Endocrine Abstracts

Background: There is increasing evidence that aldosterone exerts deleterious, blood pressure independent effects on cerebral blood vessels. We aimed to evaluate whether high aldosterone levels are related to fatal stroke.Methods: Serum aldosterone concentrations (SAC, pg/ml) were measured in 3073 Caucasian patients, who were routinely referred to coronary angiography. We calculated Cox proportional hazard ratios for death due to fatal stroke according to...

Background: The renin-angiotensin-aldosterone-system (RAAS) is a major regulator of blood pressure, however, there are no studies available addressing its characterization in a large clinical setting. Therefore, the aim of the present study was to describe the relationship between parameters of the RAAS and actual blood pressure results in a large cohort of patients with and without essential hypertension.Methods: We investigated 3253 patients (ages 63.2...